Limited information is available on carcinogenicity of asbestos on non-respiratory organs. We aimed at conducted an updated systematic review and meta-analysis of cohort studies on occupational exposure to asbestos and risk of kidney cancer. We searched through three databases, PubMed, Embase and Scopus for article published after 2000, and after eliminating duplicates and non-relevant studies, we identified 13 studies. We combined their results with those of 31 non-overlapping studies included in a previous review up to 2000. We conducted a meta-analysis based on random-effects models. The pooled relative risk of kidney cancer for asbestos exposure was 0.94 (95% confidence interval, 0.84–1.04), with no differences according to type of asbestos fiber, geographic region, period of exposure, or estimated quality of the study. Our results showed a lack of association between occupational asbestos exposure and risk of kidney cancer.

关于石棉对非呼吸器官的致癌性的信息有限。我们的目的是对职业接触石棉和肾癌风险的队列研究进行更新的系统回顾和荟萃分析。我们检索了 PubMed、Embase 和 Scopus 三个数据库，查找 2000 年之后发表的文章，在消除重复和不相关的研究后，我们确定了 13 项研究。我们将他们的结果与 2000 年以前的综述中包含的 31 项非重叠研究的结果结合起来。我们基于随机效应模型进行了荟萃分析。石棉暴露导致肾癌的汇总相对风险为 0.94（95% 置信区间，0.84-1.04），根据石棉纤维类型、地理区域、暴露时间或研究估计质量没有差异。我们的结果表明职业石棉暴露与肾癌风险之间缺乏关联。