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Autism and attention‐deficit/hyperactivity disorder in children with cerebral palsy: high prevalence rates in a population‐based study
Developmental Medicine & Child Neurology ( IF 3.8 ) Pub Date : 2020-11-18 , DOI: 10.1111/dmcn.14736
Magnus Påhlman 1, 2 , Christopher Gillberg 1 , Kate Himmelmann 2, 3
Affiliation  

AIM To assess a total population of school-age children with cerebral palsy (CP) for autism and attention-deficit/hyperactivity disorder (ADHD) with a view to determining their prevalence and to relate findings to motor function, intellectual disability, and other associated impairments. METHOD Of 264 children, born between 1999 and 2006, from the CP register of western Sweden, 200 children (109 males, 91 females, median age at assessment 14y, range 7-18y) completed comprehensive screening and further neuropsychiatric clinical assessments. RESULTS Ninety children (45%) were diagnosed with autism, ADHD, or both, 59 (30%) were diagnosed with autism, and 60 (30%) were diagnosed with ADHD. Intellectual disability was present in 51%. Two-thirds had autism, ADHD, and/or intellectual disability. In regression models, autism was mainly predicted by intellectual disability (odds ratio [OR]=4.1) and ADHD (OR=3.2), and ADHD was predicted by intellectual disability (OR=2.3) and autism (OR=3.0). Autism was more common in children born preterm (OR=2.0). Gross motor function was not associated with autism. ADHD prevalence was low in children with severe motor impairment, possibly due to diagnostic limitations. INTERPRETATION Autism and ADHD were common in this population of children with CP and were mainlyindependent of motor severity and CP type. The strongest predictor of autism/ADHD was intellectual disability. Assessment for autism and ADHD is warranted as part of the evaluation in CP.

中文翻译:

脑瘫儿童的自闭症和注意力缺陷/多动障碍:基于人群的研究中的高患病率

目的 评估患有自闭症和注意力缺陷/多动障碍 (ADHD) 的学龄脑瘫 (CP) 儿童的总人口,以确定他们的患病率并将发现与运动功能、智力障碍和其他相关损伤。方法 在瑞典西部 CP 登记册中出生于 1999 年至 2006 年的 264 名儿童中,200 名儿童(109 名男性,91 名女性,评估时的中位年龄为 14 岁,范围为 7-18 岁)完成了全面筛查和进一步的神经精神病学临床评估。结果 90 名儿童 (45%) 被诊断为自闭症、多动症或两者,59 名 (30%) 被诊断为自闭症,60 名 (30%) 被诊断为多动症。51% 存在智力障碍。三分之二的人患有自闭症、多动症和/或智力障碍。在回归模型中,自闭症主要由智力障碍(OR=4.1)和ADHD(OR=3.2)预测,ADHD由智力障碍(OR=2.3)和孤独症(OR=3.0)预测。自闭症在早产儿中更为常见(OR=2.0)。粗大运动功能与自闭症无关。严重运动障碍儿童的 ADHD 患病率较低,可能是由于诊断限制。解释 自闭症和多动症在这群 CP 儿童中很常见,并且主要与运动严重程度和 CP 类型无关。自闭症/多动症的最强预测因素是智力障碍。对自闭症和 ADHD 的评估是 CP 评估的一部分。自闭症在早产儿中更为常见(OR=2.0)。粗大运动功能与自闭症无关。严重运动障碍儿童的 ADHD 患病率较低,可能是由于诊断限制。解释 自闭症和多动症在这群 CP 儿童中很常见,并且主要与运动严重程度和 CP 类型无关。自闭症/多动症的最强预测因素是智力障碍。对自闭症和 ADHD 的评估是 CP 评估的一部分。自闭症在早产儿中更为常见(OR=2.0)。粗大运动功能与自闭症无关。严重运动障碍儿童的 ADHD 患病率较低,可能是由于诊断限制。解释 自闭症和多动症在这群 CP 儿童中很常见,并且主要与运动严重程度和 CP 类型无关。自闭症/多动症的最强预测因素是智力障碍。对自闭症和 ADHD 的评估是 CP 评估的一部分。自闭症/多动症的最强预测因素是智力障碍。对自闭症和 ADHD 的评估是 CP 评估的一部分。自闭症/多动症的最强预测因素是智力障碍。对自闭症和 ADHD 的评估是 CP 评估的一部分。
更新日期:2020-11-18
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