On March 11, 2020, the World Health Organization (WHO) declared COVID-19 a pandemic. The outbreak caused a worldwide impact, becoming a health threat to the general population and its professionals. To date, there are no specific antiviral treatments or vaccines for the COVID-19 infection, however, some drugs are being clinically tested. The use of these drugs on large scale raises great concern about their imminent environmental risk, since the elimination of these compounds by feces and urine associated with the inefficiency of sewage treatment plants in their removal can result in their persistence in the environment, putting in risk the health of humans and of other species. Thus, the goal of this work was to conduct a review of other studies that evaluated the presence of the drugs chloroquine, hydroxychloroquine, azithromycin, ivermectin, dexamethasone, remdesivir, favipiravir and some HIV antivirals in the environment. The research indicated the presence of these drugs in the environment in different regions, with concentration data that could serve as a basis for further comparative studies following the pandemic.

2020 年 3 月 11 日，世界卫生组织 (WHO) 宣布 COVID-19 为大流行病。此次疫情爆发造成了世界范围的影响，对普通民众及其专业人员的健康构成威胁。迄今为止，尚无针对 COVID-19 感染的特定抗病毒治疗方法或疫苗，但一些药物正在接受临床测试。这些药物的大规模使用引起了人们对其迫在眉睫的环境风险的高度关注，因为污水处理厂去除这些化合物的效率低下，通过粪便和尿液消除这些化合物可能会导致它们在环境中持续存在，从而带来风险人类和其他物种的健康。因此，这项工作的目标是对其他研究进行回顾，这些研究评估了环境中氯喹、羟氯喹、阿奇霉素、伊维菌素、地塞米松、瑞德西韦、法匹拉韦和一些艾滋病毒抗病毒药物的存在情况。该研究表明这些药物存在于不同地区的环境中，其浓度数据可以作为大流行后进一步比较研究的基础。