COVID-19 was a trending topic all year long in 2020. Currently, it is not only a problem for a pulmonologist since it could cause complications to many other organs, including the cardiovascular system. Recent acute COVID-19 infection state has been associated with hypercoagulation and causing microthrombi called immunothrombus. Acute limb ischemia is one of the rare complications but organ-threatening. Unfortunately, unlike coronary artery disease, there is no recent guideline for cardiologists to diagnose and manage acute limb ischemia in pandemic situations This case series presented two patients with acute limb injury (ALI)-complicating COVID-19, with chief complaints of pain at their lower extremity. The first patient was an 80-year-old woman who was just dismissed from the hospital due to COVID-19. The distal part of her toe was cyanosed, and her motoric and sensory functions were partially reduced. She was treated with oral drug therapy due to unwillingness to be hospitalized. Interestingly, she had recovered by using oral drug therapy. The second case was a 54-years-old female with several comorbidities such as obesity, type 2 diabetes mellitus, hypertension, dyslipidemia, and chronic obstructive pulmonary disease. She had cyanosed foot and weak arterial pulsation. Unfortunately, she passed away due to acute respiratory distress syndrome. Several internal and external factors cause ALI treatment to be more challenging in the pandemic COVID-19 situation. The diagnosis and management of ALI in COVID-19 patients may not fully comply with the current guideline and are likely to be affected by local hospital regulations. Clinical follow-up might be an essential feature in treating ALI in COVID-19 patients.

中文翻译：

---

COVID-19 相关急性肢体缺血的临床病例系列：真实情况

COVID-19 是 2020 年全年的热门话题。目前，这不仅是肺科医生的问题，因为它可能导致包括心血管系统在内的许多其他器官出现并发症。最近的急性 COVID-19 感染状态与高凝状态有关，并导致称为免疫血栓的微血栓。急性肢体缺血是罕见的并发症之一，但会危及器官。不幸的是，与冠状动脉疾病不同，最近没有心脏病专家在大流行情况下诊断和管理急性肢体缺血的指南 本病例系列介绍了两名患有急性肢体损伤 (ALI) 的 COVID-19 并发症患者，他们的主诉是疼痛下肢。第一位患者是一名 80 岁的妇女，她刚刚因 COVID-19 被医院解雇。她脚趾的远端发绀，她的运动和感觉功能部分减弱。因不愿住院接受口服药物治疗。有趣的是，她通过口服药物治疗康复了。第二个病例是一名 54 岁女性，患有肥胖、2 型糖尿病、高血压、血脂异常和慢性阻塞性肺病等多种合并症。她有紫绀的脚和微弱的动脉搏动。不幸的是，她因急性呼吸窘迫综合征去世了。一些内部和外部因素导致 ALI 治疗在 COVID-19 大流行的情况下更具挑战性。COVID-19 患者 ALI 的诊断和管理可能不完全符合当前指南，并可能受到当地医院法规的影响。