Background: Food allergy (FA) in children impacts their own and their family quality of life (QoL). The association of specific FA factors with the various domains of health-related QoL (HRQL) in children is unclear. Objective: The aim of this study was to evaluate FA characteristics in primary school children as determinants of components of HRQL. Methods: Children with FA were recruited from the allergy clinic of a tertiary children’s hospital. Demographic and clinical data were retrieved from their records, and 3 HRQL questionnaires were administered: the FA QoL Questionnaire-Child Form (FAQLQ-CF), the FA independent measure (FAIM), and the Pediatric QoL Questionnaire (PedsQL™). Stepwise multiple linear regression analysis was carried out to investigate the correlation between FA characteristics and the scores on the HRQL scales. Bonferroni correction for multiple comparisons was set at p #x3c; 0.0002. Results: Of 172 primary schoolchildren with FA invited to take part, 110 participated (response rate 64%), of whom 83 (75.5%) were male, aged 7.5–12.3 years (mean 10.0 ± 1.4) years. From 38 demographic and clinical characteristics, 10 were excluded on initial data analysis and 28 proceeded to bivariate analysis with the scores on FAQLQ-CF, FAIM, PedsQL™, and their subscales. Most of the 28 showed no correlation with the scores; only 4 were entered into multivariate analysis with FAQLQ-CF and PedsQL™ scores, none of which, finally showed significant association. Conclusion: The HRQL of children with FA did not depend on gender, age, number, and type of allergen or the characteristics of the most severe allergic reaction.
Int Arch Allergy Immunol

中文翻译：

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食物过敏儿童生活质量决定因素调查

背景：儿童食物过敏 (FA) 会影响他们自己和家庭的生活质量 (QoL)。特定 FA 因素与儿童健康相关 QoL (HRQL) 各个领域的关联尚不清楚。目的：本研究的目的是评估小学生的 FA 特征作为 HRQL 组成部分的决定因素。方法：从三级儿童医院的过敏诊所招募患有 FA 的儿童。从他们的记录中检索人口统计学和临床​​数据，并管理了 3 份 HRQL 问卷：FA QoL 问卷 - 儿童表 (FAQLQ-CF)、FA 独立测量 (FAIM) 和小儿 QoL 问卷 (PedsQL™)。进行逐步多元线性回归分析以研究 FA 特征与 HRQL 量表分数之间的相关性。多重比较的 Bonferroni 校正设置为p #x3c；0.0002。结果：在受邀参加的 172 名 FA 小学生中，有 110 名参加（响应率 64%），其中 83 名（75.5%）为男性，年龄 7.5-12.3 岁（平均 10.0 ± 1.4）岁。从 38 个人口统计学和临床​​特征中，10 个在初始数据分析中被排除，28 个进行双变量分析，对 FAQLQ-CF、FAIM、PedsQL™ 及其子量表进行评分。28 个中的大多数与分数没有相关性；只有 4 项通过 FAQLQ-CF 和 PedsQL™ 分数进行多变量分析，最终均未显示出显着关联。结论： FA患儿的HRQL与性别、年龄、数量、过敏原类型或最严重过敏反应的特征无关。
Int Arch 过敏免疫