Purpose: To investigate whether the degree of asthma control is associated with anemia in pediatric patients.
Patients and Methods: A cross-sectional study was performed using a dataset from the Health Insurance Reviews & Assessment Service (HIRA) of South Korea in 2016, which included children and adolescent patients diagnosed with asthma. Binary logistic regression was used to assess the association between asthma control and the prevalence of anemia.
Results: A total of 236,429 patients under 18 years old were included in the study, including 233,975 patients with controlled and 2454 with uncontrolled asthma. Binary logistic regression after adjustment for confounding factors showed that patients with uncontrolled asthma had a 2.64-fold higher prevalence of anemia than those with well-controlled asthma (OR = 2.64, 95% CI: 2.16– 3.22). While there was no effect of gender on the results, there was a statistically significant association between the prevalence of anemia and asthma control in patients under 13 years old.
Conclusion: These findings suggest that the prevalence of anemia is inversely correlated with asthma control in pediatric patients. Further studies are necessary to obtain pathophysiological insight into the relationship between severe inflammatory diseases and anemia.

Keywords: pediatric, asthma, anemia, anemia of inflammation, iron deficiency anemia


中文翻译：

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根据哮喘控制的儿科患者贫血患病率：倾向评分分析

目的：调查哮喘控制程度是否与儿科患者的贫血有关。
患者和方法：使用 2016 年韩国健康保险审查和评估服务 (HIRA) 的数据集进行了一项横断面研究，其中包括被诊断患有哮喘的儿童和青少年患者。二元逻辑回归用于评估哮喘控制与贫血患病率之间的关联。
结果：该研究共纳入 236,429 名 18 岁以下患者，其中哮喘控制患者 233,975 人，哮喘未控制患者 2454 人。调整混杂因素后的二元逻辑回归显示，哮喘未控制患者的贫血患病率比哮喘控制良好的患者高 2.64 倍（OR = 2.64，95% CI：2.16-3.22）。虽然性别对结果没有影响，但 13 岁以下患者的贫血患病率与哮喘控制之间存在统计学显着关联。
结论：这些研究结果表明，贫血的患病率与儿科患者的哮喘控制呈负相关。需要进一步的研究来获得对严重炎症性疾病与贫血之间关系的病理生理学见解。

关键词：儿童，哮喘，贫血，炎症性贫血，缺铁性贫血