ABSTRACT

The study aimed to describe the progression of state anxiety in adolescents with anorexia nervosa (AN) hospitalized on a high calorie refeeding (HCR) protocol. Participants, 12–21 years, admitted for malnutrition due to AN were placed on a HCR protocol in which calories were advanced by 300 kcal/day. The State-Trait Anxiety Inventory for Children (STAIC) was given to participants within 24 hours of hospitalization and the state anxiety component of the STAIC was administered daily immediately before and after breakfast until discharge. Of 22 patients enrolled, 86% were female, mean age was 14.9 ± 2.0 years, and 95% had AN-restrictive type. The median state and trait anxiety scores at time of admission were 37.0 (28–55) and 35.5 (23–51), respectively. There was no significant difference in median pre-meal state anxiety from hospital day 1 to 6 (34.0(26–55) vs. 38.5(25–55), p-value = 0.079) or in median post-meal state anxiety from hospital day 1 to 6 (35.5(29–56) vs. 37(24–56), p-value = 0.484). Similarly, we found minimal correlation between change in caloric intake and change in pre-meal S-anxiety (Spearman correlation coefficient = −0.032) or post-meal S-anxiety (Spearman correlation = 0.032). While this was a small sample observing anxiety over one week, we found no evidence that state anxiety increased with advancing calories, providing additional support for the use of more rapid refeeding protocols.

摘要

该研究旨在描述接受高热量再喂养 (HCR) 方案住院的神经性厌食症 (AN) 青少年状态焦虑的进展。因 AN 导致营养不良入院的 12-21 岁参与者被置于 HCR 方案中，其中热量增加了 300 kcal/天。在住院后 24 小时内向参与者提供儿童状态特征焦虑量表 (STAIC)，并在每天早餐前后立即给予 STAIC 的状态焦虑成分直至出院。在入组的 22 名患者中，86% 为女性，平均年龄为 14.9 ± 2.0 岁，95% 为 AN 限制型。入院时的中位状态和特质焦虑评分分别为 37.0 (28-55) 和 35.5 (23-51)。从住院第 1 天到第 6 天，餐前状态焦虑的中位数没有显着差异（34.p值 = 0.079）或住院第 1 天至第 6 天的中位餐后状态焦虑（35.5（29-56）对 37（24-56），p值 = 0.484）。同样，我们发现热量摄入的变化与餐前 S-焦虑（Spearman 相关系数 = -0.032）或餐后 S-焦虑（Spearman 相关 = 0.032）的变化之间的相关性很小。虽然这是一个观察一周内焦虑的小样本，但我们没有发现任何证据表明状态焦虑会随着卡路里的增加而增加，这为使用更快速的再喂养方案提供了额外的支持。