The alleged primary mechanism underlying bleeding events associated with antidepressants is inhibition of serotonin uptake in platelets resulting in reduced platelet aggregability and activity, and prolonged bleeding time. There is some evidence that a substance's degree of serotonin reuptake inhibition in terms of its binding affinity to the serotonin transporter (SERT) affects the magnitude of bleeding risk increase.

中文翻译：

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血清素转运蛋白结合亲和力对抗抑郁药相关出血风险的影响。

据称与抗抑郁药相关的出血事件的主要机制是抑制血小板中血清素的摄取，导致血小板聚集性和活性降低，并延长出血时间。有一些证据表明，就其与血清素转运蛋白 (SERT) 的结合亲和力而言，一种物质对血清素再摄取的抑制程度会影响出血风险增加的幅度。