Percentage of Gleason pattern 4 and tumor volume predict adverse pathological stage and margin status at radical prostatectomy in grade Group 2 and grade Group 3 prostate cancers,The Prostate

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Percentage of Gleason pattern 4 and tumor volume predict adverse pathological stage and margin status at radical prostatectomy in grade Group 2 and grade Group 3 prostate cancers
The Prostate ( IF 2.6 ) Pub Date : 2021-06-29 , DOI: 10.1002/pros.24183
Oleksii A Iakymenko ₁ , Isabella Lugo ₁ , Laurence M Briski _{1,

2} , Ivan Nemov ₁ , Sanoj Punnen _{2,

3} , Deukwoo Kwon ₄ , Alan Pollack _{2,

5} , Radka Stoyanova _{2,

5} , Dipen J Parekh _{2,

3} , Merce Jorda _{1,

2,

3} , Mark L Gonzalgo _{2,

3} , Oleksandr N Kryvenko _{1,

2,

3}

Affiliation

Increasing percentages of Gleason pattern 4 (GP4%) in radical prostatectomy (RP) correlate with an increased likelihood of nonorgan-confined disease and earlier biochemical recurrence (BCR). However, there are no detailed RP studies assessing the impact of GP4% and corresponding tumor volume (TV) on extraprostatic extension (EPE), seminal vesicle (SV) invasion (SV+), and positive surgical margin (SM) status (SM+).

中文翻译：

Gleason 模式 4 的百分比和肿瘤体积预测 2 级和 3 级前列腺癌根治性前列腺切除术的不良病理分期和切缘状态

根治性前列腺切除术 (RP) 中格里森模式 4 (GP4%) 的百分比增加与非器官局限疾病和早期生化复发 (BCR) 的可能性增加相关。然而，没有详细的 RP 研究评估 GP4% 和相应的肿瘤体积 (TV) 对前列腺外延伸 (EPE)、精囊 (SV) 侵袭 (SV+) 和手术切缘阳性 (SM) 状态 (SM+) 的影响。

更新日期：2021-07-20

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