ABSTRACT

Background

Morning blood pressure surge (MBPS) plays an important role in target organ damage and major adverse cardiac events. The frontal QRS-T [f(QRS-T)] angle is the electrocardiographic marker and index of ventricular arrhythmogenic events. We aimed to investigate the relationship between MBPS and the f(QRS-T) angle, which is an indicator of ventricular repolarization disorder, in patients with newly diagnosed HT.

Methods

Between June 2020 and March 2021, 263 patients with newly diagnosed HT who were admitted to our outpatient clinic were prospectively included in the study. According to ambulatory blood pressure monitoring (ABPM), the patients were categorized into two groups: Group-I: low-value MBPS (<37 mm Hg), and group-II: high-value MBPS (≥37 mm Hg). The f(QRS-T) angle calculated from the 12-lead electrocardiogram and all other data were compared between the groups.

Results

A total of 186 newly diagnosed HT patients who met the inclusion criteria were included in the study. The average f(QRS-T) angle in Groups I and 2 was 21° ± 16° and 51° ± 30°, respectively (P < .001). According to multivariate regression analysis, T peak-end and MBPS were found to be independent predictors of the f(QRS-T) angle.

Conclusions

As a result of our study, we found that the f(QRS-T) angle was widened in patients with exaggerated MBPS. The cause of increased cardiovascular outcomes in patients with exaggerated MBPS may be explained by widened in the f(QRS-T) angle that is a ventricular repolarization parameter.

中文翻译：

---

初诊高血压患者晨间血压波动与额平面QRS-T角的关系

摘要

背景

晨间血压升高 (MBPS) 在靶器官损害和主要心脏不良事件中起重要作用。额叶 QRS-T [f(QRS-T)] 角是心电图标志物和室性心律失常事件的指标。我们旨在研究新诊断的 HT 患者的 MBPS 与 f(QRS-T) 角之间的关系，f(QRS-T) 角是心室复极障碍的指标。

方法

在 2020 年 6 月至 2021 年 3 月期间，263 名新诊断的 HT 患者被前瞻性纳入我们的门诊。根据动态血压监测（ABPM），将患者分为两组：第一组：低值MBPS（<37 mm Hg），第二组：高值MBPS（≥37 mm Hg）。从 12 导联心电图计算的 f(QRS-T) 角和所有其他数据在组间进行比较。

结果

共有 186 名符合纳入标准的新诊断 HT 患者被纳入研究。第 I 组和第 2 组的平均 f(QRS-T) 角分别为 21° ± 16° 和 51° ± 30° ( P < .001)。根据多元回归分析，发现 T 峰端和 MBPS 是 f(QRS-T) 角的独立预测因子。

结论

作为我们研究的结果，我们发现夸大 MBPS 患者的 f(QRS-T) 角变宽。夸大 MBPS 患者心血管结局增加的原因可能是心室复极参数 f(QRS-T) 角变宽所致。