Abstract

The interhemispheric signal propagation (ISP) obtained by electroencephalography during transcranial magnetic stimulation (TMS) allows for the assessment of the interhemispheric connectivity involved in inhibitory processes. To investigate the functional asymmetry of hemispheres during rapid movement, we compared ISP in the left and right hemispheres during rapid hand movements. In 11 healthy right-handed adults, we delivered TMS to the M1 and recorded ISP from the M1 to the contralateral hemisphere. We found that ISP from the left to right hemisphere during right-hand rapid movement was higher than ISP from the right to left hemisphere during the left-hand rapid movement. These results indicate that the left M1 strongly inhibits the right M1, and that the left hemisphere is dominant for rapid movements as well as sequential movements.

摘要

在经颅磁刺激 (TMS) 期间通过脑电图获得的大脑半球间信号传播 (ISP) 允许评估参与抑制过程的大脑半球间连通性。为了研究快速运动过程中大脑半球的功能不对称性，我们比较了快速手部运动过程中左右半球的 ISP。在 11 名健康的右利手成年人中，我们将 TMS 传送到 M1 并记录从 M1 到对侧半球的 ISP。我们发现右手快速运动时从左到右半球的 ISP 高于左手快速运动时从右到左半球的 ISP。这些结果表明左侧 M1 强烈抑制右侧 M1，并且左半球在快速运动和连续运动中占主导地位。