当前位置: X-MOL 学术Nat. Rev. Genet. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Quantifying the effect of reference genome choice
Nature Reviews Genetics ( IF 39.1 ) Pub Date : 2021-06-28 , DOI: 10.1038/s41576-021-00392-2
Darren Burgess 1
Affiliation  

A study in the American Journal of Human Genetics shows that using the GRCh37 versus GRCh38 version of the human reference genome makes a meaningful difference to the calling of human genetic variants, with implications for research-based and clinical-based human sequencing studies.

中文翻译:

量化参考基因组选择的影响

《美国人类遗传学杂志》上的一项研究表明,使用人类参考基因组的 GRCh37 与 GRCh38 版本对人类遗传变异的调用产生了有意义的差异,对基于研究和基于临床的人类测序研究具有意义。
更新日期:2021-06-28
down
wechat
bug