The molecular pathophysiology of diabetes in pancreatic islets remains largely a poorly understood ‘black box’ because of the inaccessibility of pancreatic tissue from living humans for molecular analysis. Wigger et al. now explore the transcriptional and proteomic profiles of pancreatic islet sections from people whose glucose tolerance was defined before pancreatic surgery during which a small portion of their pancreata became available for study.

中文翻译：

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达到 2 型糖尿病的方法不止一种

胰岛糖尿病的分子病理生理学在很大程度上仍然是一个知之甚少的“黑匣子”，因为无法对活人的胰腺组织进行分子分析。维格等人。现在探索胰岛切片的转录和蛋白质组学概况，这些人的葡萄糖耐量在胰腺手术前定义，在此期间他们的一小部分胰腺可用于研究。