A method for the synthesis of 1,3-dialkyl-4-[(arylmethylidene)amino]glycolurils was developed based on nucleophilic substitution of the sulfur atom with the oxygen atom in the corresponding thioglycolurils via alkylation of the latter followed by acid hydrolysis of alkylsulfanyl derivatives of thioglycolurils, both with the isolation of alkylsulfanyl intermediates and by the one-pot method. The structure of the synthesized compounds was confirmed by X-ray structural analysis of several examples.

中文翻译：

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1,3-二烷基-4-[(芳基亚甲基)氨基]甘脲的合成

开发了一种合成 1,3-二烷基-4-[(芳基亚甲基)氨基]甘脲的方法，该方法基于硫原子与相应硫甘脲中的氧原子的亲核取代，通过后者的烷基化，然后烷基硫烷基的酸水解巯基脲衍生物，包括烷基硫基中间体的分离和一锅法。合成化合物的结构通过几个实施例的 X 射线结构分析得到证实。