Inflammation is a marker of arterial disease stemming from cholesterol-dependent to -independent molecular mechanisms. In recent years, the role of inflammation in atherogenesis has been underpinned by pharmacological approaches targeting systemic inflammation that have led to a significant reduction in cardiovascular disease (CVD) risk. Although the use of nutraceuticals to prevent CVD has largely focused on lipid-lowering (e.g, red-yeast rice and omega-3 fatty acids), there is growing interest and need, especially now in the time of coronavirus pandemic, in the use of nutraceuticals to reduce inflammatory markers, and potentially the inflammatory CVD burden, however, there is still not enough evidence to confirm this. Indeed, diet is an important lifestyle determinant of health and can influence both systemic and vascular inflammation, to varying extents, according to the individual nutraceutical constituents. Thus, the aim of this Position Paper is to provide the first attempt at recommendations on the use of nutraceuticals with effective anti-inflammatory properties.

炎症是动脉疾病的标志物，其源于胆固醇依赖性至非依赖性分子机制。近年来，炎症在动脉粥样硬化中的作用得到了靶向全身炎症的药理学方法的支持，这些方法导致心血管疾病 (CVD) 风险显着降低。尽管使用营养食品来预防 CVD 主要集中在降脂（例如，红曲米和 omega-3 脂肪酸），人们对使用营养食品来减少炎症标志物和潜在的炎症性心血管疾病负担的兴趣和需求越来越大，尤其是现在在冠状病毒大流行时期，但是，仍然存在没有足够的证据来证实这一点。事实上，饮食是健康的重要生活方式决定因素，根据个体营养成分的不同，可以在不同程度上影响全身和血管炎症。因此，本立场文件的目的是首次尝试就使用具有有效抗炎特性的营养食品提出建议。