Describe the complications associated with surgical resection of primary apocrine gland anal sac adenocarcinoma (AGASACA) tumours study design multi-institutional retrospective cross-sectional cohort study Animals Client owned dogs with spontaneous disease using the Clavien-Dindo classification system, post-operative events were assigned and described. Logistic regression analysis was used to analyse for risk factors for a significant association with complications. One hundred sixty-one dogs were included in the analysis. The post-operative sequelae, complication, and failure to cure rates specific to the anal sac site was 14%, 17% and 1%, respectively. The majority (68%) of complications were grade II or higher, therefore requiring some form of intervention. Intra-operative complications were identified in 11 cases (7%) with anorectal wall perforation being most common. An intra-operative complication was significantly associated with post-operative complications (p < 0.001; OR 7.4) while anorectal wall perforation was the only significant risk factor on regression analysis (p < 0.001; OR 19). Surgical site infection was identified in 20 of 161 (12%) of cases. Local recurrence (LR) occurred in 18% of cases at a median of 374 days (95% CI: 318–430). The only risk factor significantly associated with LR was the presence of vascular or lymphatic invasion (p = 0.008; OR 3). Post-operative complications were relatively infrequent but the risk was significantly increased when there was an intraoperative complication during resection of a primary AGASACA tumour. This study provides information for the clinician regarding risk factors for post-operative complications.

中文翻译：

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犬大汗腺肛门囊腺癌切除术后并发症

描述与手术切除原发性大汗腺肛门囊腺癌 (AGASACA) 肿瘤相关的并发症 研究设计 多机构回顾性横断面队列研究 动物 客户拥有的患有自发性疾病的狗使用 Clavien-Dindo 分类系统，分配了术后事件并描述。逻辑回归分析用于分析与并发症显着相关的危险因素。分析中包括 161 只狗。肛囊部位的术后后遗症、并发症和治愈失败率分别为 14%、17% 和 1%。大多数 (68%) 并发症为 II 级或更高级别，因此需要某种形式的干预。在 11 例（7%）中发现了术中并发症，其中肛门直肠壁穿孔最为常见。术中并发症与术后并发症显着相关（p < 0.001；OR 7.4），而肛门直肠壁穿孔是回归分析中唯一显着的危险因素（p < 0.001；OR 19）。161 例（12%）病例中有 20 例发现手术部位感染。18% 的病例发生局部复发 (LR)，中位时间为 374 天 (95% CI: 318-430)。与 LR 显着相关的唯一危险因素是存在血管或淋巴浸润（p = 0.008；OR 3）。术后并发症相对较少，但在原发性 AGASACA 肿瘤切除过程中出现术中并发症时风险显着增加。