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Extracellular vesicles of Echinococcus granulosus have therapeutic effects in allergic airway inflammation
Parasite Immunology ( IF 1.4 ) Pub Date : 2021-06-26 , DOI: 10.1111/pim.12872
Mi Jin Jeong 1 , Shin Ae Kang 1 , Jun Ho Choi 1 , Da In Lee 1 , Hak Sun Yu 1, 2
Affiliation  

Previous studies have shown that Echinococcus granulosus cystic fluid can alleviate Th2 allergic airway inflammatory responses by increasing the number of CD4+CD25+ Foxp3+T (regulatory T; Treg) cells. Parasite-derived extracellular vesicles (EV) are known to not only promote parasite infection by communicating between parasites but also regulate the inflammatory response by acting as an immunomodulatory agent in the host.

中文翻译:

细粒棘球绦虫胞外囊泡对过敏性气道炎症的治疗作用

之前的研究表明,细粒棘球绦虫囊液可以通过增加CD4 + CD25 + Foxp3 + T(regulatory T;Treg)细胞的数量来缓解Th2过敏性气道炎症反应。已知寄生虫衍生的细胞外囊泡 (EV) 不仅通过寄生虫之间的交流促进寄生虫感染,而且还通过充当宿主的免疫调节剂来调节炎症反应。
更新日期:2021-06-26
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