In ruminants, the ruminal epithelium not only has the function of absorbing nutrients but also is an important tissue to prevent harmful substances in the rumen from entering the blood circulation. Thus, the normal function of ruminal epithelium is critical for ruminants. However, subacute ruminal acidosis induced by high-concentrate diets often damages the barrier function of ruminal epithelium in ruminants. Recently, many studies have shown that dietary supplementation with thiamine is an effective method to alleviate subacute ruminal acidosis. In order to provide theoretical reference for the in-depth study of subacute ruminal acidosis and the application of thiamine in the future, this review introduces the effects of subacute ruminal acidosis on morphological structure, inflammatory response, and tight junction of ruminal epithelium. In addition, this paper summarizes the role of thiamine in maintaining ruminal epithelial function of ruminants during subacute ruminal acidosis challenge.

中文翻译：

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补充硫胺素对亚急性瘤胃酸中毒期间瘤胃上皮损伤的潜在保护作用

在反刍动物中，瘤胃上皮不仅具有吸收营养物质的功能，而且是防止瘤胃内有害物质进入血液循环的重要组织。因此，瘤胃上皮的正常功能对反刍动物至关重要。然而，高精日粮引起的亚急性瘤胃酸中毒往往会损害反刍动物瘤胃上皮的屏障功能。最近，许多研究表明，日粮中补充硫胺素是缓解亚急性瘤胃酸中毒的有效方法。为了为今后亚急性瘤胃酸中毒的深入研究和硫胺素的应用提供理论参考，本文就亚急性瘤胃酸中毒对瘤胃上皮形态结构、炎症反应和紧密连接的影响进行综述。