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The Use of Atomic Force Microscopy in Comprehensive Assessment of the “Mother—Placenta—Fetus” System in Obstetric and Endocrine Pathology during Pregnancy
Bulletin of Experimental Biology and Medicine ( IF 0.9 ) Pub Date : 2021-06-26 , DOI: 10.1007/s10517-021-05206-3
T V Pavlova 1 , A I Shchegolev 2 , A N Kaplin 3 , E S Malyutina 1 , A V Selivanova 1 , L O Zemlyanskaya 1
Affiliation  

Atomic force microscopy is not very popular in practical health care, therefore, its potential is not studied enough, for example, in obstetrics when studying the “mother—placenta—fetus” system. Our study summarizes the possibilities of using atomic force microscopy for detection of various circulatory disorders and vascular changes at the microscopic level in the uterus (endometrium and myometrium), placenta, and umbilical cord in the main variants of obstetric and endocrine pathology. For instance, in the case of endocrine pathologies, changes in the form of stasis, sludge, diapedesis, ischemia, destruction and separation of endotheliocytes in villous blood vessels were found in the mother. The oxygen content in erythrocytes also naturally decreased in pathologies; poikilo- and anisocytosis were observed.



中文翻译:

原子力显微镜在孕期产科内分泌病理学“母-胎-胎”系统综合评估中的应用

原子力显微镜在实际医疗保健中不是很普及,因此对其潜力的研究还不够,例如在产科研究“母亲-胎盘-胎儿”系统时。我们的研究总结了在产科和内分泌病理学的主要变体中使用原子力显微镜在子宫(子宫内膜和子宫肌层)、胎盘和脐带的微观水平上检测各种循环障碍和血管变化的可能性。例如,在内分泌疾病的情况下,母亲的绒毛血管中的内皮细胞出现淤滞、淤泥、血肿、缺血、破坏和分离等形式的变化。红细胞中的氧含量在病理情况下也会自然降低;观察到异红细胞和异红细胞增多症。

更新日期:2021-06-28
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