当前位置: X-MOL 学术Bull. Exp. Biol. Med. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Morphogenetic Aspects of the Response of Vaginal Tissues to Polypropylene Implants as the Basis of Mesh-Associated Complications
Bulletin of Experimental Biology and Medicine ( IF 0.7 ) Pub Date : 2021-06-26 , DOI: 10.1007/s10517-021-05209-0
I A Eisenach 1 , A K Pichigina 1 , G A Lapii 1 , V G Mozes 2
Affiliation  

Morphometric and immunohistochemical examination of the vaginal mucosa before and 12 months after installation of polypropylene implants for the correction of stress urinary incontinence was performed in 20 patients with genital prolapse. The research results confirmed good biocompatibility of polypropylene and the formation of full-fledged connective tissue in the vaginal mucosa, but revealed the presence of a weak lymphocytic reaction to polypropylene 12 months after surgery. According to immunohistochemical study, increased contents of B lymphocytes and plasma cells responsible for the inductive and productive stages of the immune response were revealed in the vaginal mucosa around the implants 12 months after surgery. This reaction in the presences of provoking factors can lead to the development of inflammation and erosion, a type of mesh-associated complications.



中文翻译:

阴道组织对聚丙烯植入物反应的形态发生方面是网状相关并发症的基础

对 20 名生殖器脱垂患者在安装聚丙烯植入物以矫正压力性尿失禁之前和之后 12 个月对阴道粘膜进行形态测量和免疫组织化学检查。研究结果证实聚丙烯具有良好的生物相容性,并且在阴道粘膜中形成了成熟的结缔组织,但在手术后 12 个月显示出对聚丙烯的弱淋巴细胞反应。根据免疫组织化学研究,术后 12 个月,植入物周围的阴道黏膜中发现负责免疫反应诱导和生产阶段的 B 淋巴细胞和浆细胞含量增加。这种在刺激因素存在下的反应会导致炎症和侵蚀的发展,

更新日期:2021-06-28
down
wechat
bug