While many aspects of female ovarian function respond to environmental stressors, estradiol (E2) appears less sensitive to stressors than progesterone, except under extreme ecological conditions. However, earlier studies relied on saliva samples, considered less sensitive than blood. Here, we investigated E2 variation among 177 Bangladeshi and UK white women, aged 35–59, using single serum samples. Bangladeshi women either grew up in Sylhet, Bangladesh (exposed to poor sanitation, limited health care, and higher pathogen loads but not poor energy availability), or in the UK.

中文翻译：

---

发育状况对英国和孟加拉孟加拉妇女血清雌二醇水平没有影响

虽然女性卵巢功能的许多方面对环境压力有反应，但雌二醇 (E2) 对压力的敏感性似乎不如黄体酮，除非在极端生态条件下。然而，早期的研究依赖于唾液样本，被认为不如血液敏感。在这里，我们使用单一血清样本调查了 177 名 35-59 岁的孟加拉国和英国白人女性的 E2 变异。孟加拉妇女要么在孟加拉锡尔赫特长大（卫生条件差、医疗保健有限、病原体负荷高，但能源供应不差），要么在英国长大。