当前位置: X-MOL 学术Mech. Ageing Dev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Objectively assessed physical activity and sedentary behavior and global cognitive function in older adults: a systematic review
Mechanisms of Ageing and Development ( IF 5.3 ) Pub Date : 2021-06-25 , DOI: 10.1016/j.mad.2021.111524
Anna G M Rojer 1 , Keenan A Ramsey 1 , Elvira S Amaral Gomes 1 , Luke D'Andrea 2 , Christopher Chen 3 , Cassandra Szoeke 4 , Carel G M Meskers 5 , Esmee M Reijnierse 6 , Andrea B Maier 7
Affiliation  

Background

Both physical activity (PA) and sedentary behavior (SB) are important factors for healthy ageing. This systematic review aimed to determine the association of objectively assessed (instrumented) PA and SB with global cognitive function in older adults.

Methods

PubMed, Embase, the Cochrane Library (via Wiley), CINAHL, PsychINFO, and SPORTDiscus (via EBSCO) were searched from inception to June 21, 2020 for articles that described associations of objectively assessed PA/SB with global cognitive function in older adults aged 60 years and older. Results were synthesized using an effect direction heat map and albatross plots portrayed estimated effect sizes (standardized regression coefficients (βs)), which were summarized in boxplots.

Results

In total, 45 articles were included representing a total of 15,817 older adults (mean/median age ranged from 65 to 88 years; 49.5% female). Longitudinal studies (n = 7) showed that higher moderate-to-vigorous and light PA (MVPA and LPA, respectively) and lower SB were associated with better global cognitive function. Standardized βs of cross-sectional studies (n = 38) showed that lower SB (median [IQR], β = 0.078 [0.004-0.184] and higher LPA (β = 0.096 [0.046-0.188]), activity counts (β = 0.131 [0.049-0.224]), number of steps (β = 0.155 [0.096-0.246]), MVPA (β = 0.163 [0.069-0.285]) and total PA (TPA) (β = 0.174 [0.147-0.255]) were associated with better global cognitive function.

Conclusions

Higher PA and lower SB are associated with better global cognitive function in older adults. The greatest estimated effect sizes were found for moderate-to-vigorous and TPA, suggesting that greater duration of any PA, and high intensity PA could be most beneficial for global cognitive function.



中文翻译:

客观评估老年人的身体活动和久坐行为以及整体认知功能:系统评价

背景

身体活动 (PA) 和久坐行为 (SB) 都是健康老龄化的重要因素。该系统评价旨在确定客观评估(仪器化)的 PA 和 SB 与老年人整体认知功能的关系。

方法

PubMed、Embase、Cochrane 图书馆(通过 Wiley)、CINAHL、PsychINFO 和 SPORTDiscus(通过 EBSCO)从开始到 2020 年 6 月 21 日进行了搜索,以寻找描述客观评估的 PA/SB 与老年人全球认知功能之间关联的文章60岁及以上。使用效果方向热图合成结果,信天翁图描绘了估计的效果大小(标准化回归系数(βs)),并在箱线图中进行了总结。

结果

共纳入 45 篇文章,代表 15,817 名老年人(平均/中位年龄范围为 65 至 88 岁;49.5% 为女性)。纵向研究(n = 7)表明,较高的中度至剧烈和轻度 PA(分别为 MVPA 和 LPA)和较低的 SB 与更好的整体认知功能相关。横断面研究的标准化 β (n = 38) 表明,较低的 SB(中位数 [IQR],β = 0.078 [0.004-0.184] 和较高的 LPA(β = 0.096 [0.046-0.188]),活动计数(β = 0.131 [0.049-0.224])、步数 (β = 0.155 [0.096-0.246])、MVPA (β = 0.163 [0.069-0.285]) 和总 PA (TPA) (β = 0.174 [0.147-0.255]) 相关具有更好的全局认知功能。

结论

较高的 PA 和较低的 SB 与老年人更好的整体认知功能相关。中度至剧烈和 TPA 的估计效果最大,这表明任何 PA 的持续时间更长,高强度 PA 可能对整体认知功能最有益。

更新日期:2021-07-16
down
wechat
bug