Biorefinery is defined as a sustainable process where biomass is converted in a spectrum of marketable products and fuels. In this view, C6 furan-based compounds, usually referred as furanics, have been extensively investigated as aromatic promising building blocks from renewables. 5-Hydroxymethylfurfural (HMF) and 2,5-furan dicarboxylic acid (FDCA) are well known examples of furanics whose syntheses and applications have been extensively reviewed in the literature. Herein for the first time it is reported a comprehensive overview on the synthetic procedures to another bio-derived furan compounds, i.e. 2,5-bis(hydroxymethyl)furan (BHMF), a stable bio-based diol with numerous applications as monomer for bio-materials and fuels. Advantages and limitations of the different synthetic approaches are addressed, as well as possible future developments to render this compound part of the biorefinery market.

中文翻译：

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2,5-双（羟甲基）呋喃 (BHMF) 的合成方法：一种稳定的生物基二醇

生物精炼被定义为一个可持续的过程，其中生物质被转化为一系列适销对路的产品和燃料。从这个角度来看，C6 呋喃类化合物（通常称为呋喃类化合物）已被广泛研究为可再生能源中的芳香族有前途的构建单元。5-羟甲基糠醛 (HMF) 和 2,5-呋喃二甲酸 (FDCA) 是众所周知的呋喃类化合物，其合成和应用已在文献中进行了广泛的综述。本文首次报道了另一种生物衍生呋喃化合物的合成程序的综合概述，即 2,5-双（羟甲基）呋喃 (BHMF)，一种稳定的生物基二醇，作为生物单体的众多应用-材料和燃料。解决了不同合成方法的优点和局限性，