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Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
Heterocyclic Communications ( IF 2.3 ) Pub Date : 2019-12-31 , DOI: 10.1515/hc-2019-0022
Shin-taro Katayama 1 , Hiroshi Nishino 1
Affiliation  

Abstract Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.

中文翻译:

螺[环己烷-1,3'-二氢吲哚]-2,2'-二酮的简便合成

摘要 通过将 N-芳基-N-甲基-2-氧代环己烷-1-甲酰胺在一锅中氧化,制备螺[环己烷-1,3'-二氢吲哚]-2,2'-二酮很容易,收率高。反应时间短。螺二氢吲哚二酮对天然产物的全合成很重要。
更新日期:2019-12-31
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