Abstract

The conjugated compound (3Z,6Z)-3,6-bis((5-(9,9-bis(2-octyldodecyl)-9H-fluoren-2-yl) thiophene-2-yl) methylene) piperazin-2,5-dione(p-QM2AF) was synthesized successfully. Nanoparticles (NPs) coated with p-QM2AF compound were prepared from liposomes. The morphology of NPs was characterized by transmission electron microscope and dynamic light scattering instrument, and the NPs maintained high stability after long time storage. Cytotoxicity test was used to evaluate the safety of nanoparticles, and the photothermal properties were characterized.

中文翻译：

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DAD共轭小分子纳米粒子的合成及光热应用

摘要

共轭化合物(3Z,6Z)-3,6-双((5-(9,9-双(2-辛基十二烷基)-9H-芴-2-基)噻吩-2-基)亚甲基)哌嗪-2， 5-二酮(p-QM2AF)合成成功。从脂质体制备涂有 p-QM2AF 化合物的纳米颗粒 (NPs)。通过透射电子显微镜和动态光散射仪对纳米颗粒的形貌进行表征，纳米颗粒在长期储存后仍保持较高的稳定性。采用细胞毒性试验评价纳米颗粒的安全性，并表征其光热性能。