Autoimmune diseases are a heterogeneous group of diseases which lose the immunological tolerance to self-antigens. It is well recognized that irregularly provoked T cells participate in the pathological immune responses. As a novel nanomaterial with promising applications, tetrahedral framework nucleic acid (TFNA) nanostructure was found to have immune regulatory effects on T cells in this study.

中文翻译：

---

四面体框架核酸通过丝裂原活化蛋白激酶途径对人T细胞的免疫调节作用

自身免疫性疾病是一组对自身抗原失去免疫耐受性的异质性疾病。众所周知，不规则激发的 T 细胞参与病理免疫反应。作为一种具有广阔应用前景的新型纳米材料，本研究发现四面体框架核酸（TFNA）纳米结构对 T 细胞具有免疫调节作用。