Emotion is defined as a response to external stimuli and internal mental representations. It has been characterized as a multidimensional concept, primarily comprising two dimensions: valence and arousal. Existing studies have demonstrated that emotional experience exerts a powerful impact on auditory processing in terms of valence. However, it has also been shown that while negative emotion can improve auditory perception in healthy subjects, patients with depression show deficits in auditory perception. We thus speculated that both arousal and valence jointly modulate auditory perception. To examine the emotion-driven effects on the auditory response, we induced positive, negative, and neutral emotional states in healthy subjects and collected auditory steady-state response (ASSR) evoked by a 40-Hz chirp sound. We calculated peak-to-peak amplitude (PPA) and event-related spectral perturbation (ERSP) of evoked ASSRs and observed that the positive emotions significantly enhanced brain responses to auditory stimuli (p <; 0.001), but that ASSRs in a negative state were not significantly enhanced compared with the neutral state. Subsequently, regression analysis showed a significant positive multiple linear relationship between the PPA and ratings of two emotional dimensions, indicating that arousal and valence jointly regulated the auditory cortex's synchronous oscillation, rather than the valence in isolation, offering the potential to clarify the conflicting results surrounding the role of negative emotions in auditory responses. Because depression is generally characterized by low arousal and low valence in actual life, whereas the negative emotion evoked under laboratory conditions is always with low valence but high arousal.

中文翻译：

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情绪唤醒和效价共同调节听觉反应：40 Hz ASSR 研究


情绪被定义为对外部刺激和内部心理表征的反应。它被描述为一个多维概念，主要包含两个维度：价和唤醒。现有研究表明，情绪体验对听觉处理的效价产生强大影响。然而，也有研究表明，虽然负面情绪可以改善健康受试者的听觉感知，但抑郁症患者却表现出听觉感知缺陷。因此，我们推测唤醒度和效价共同调节听觉感知。为了检查情绪驱动对听觉反应的影响，我们在健康受试者中诱导了积极、消极和中性情绪状态，并收集了由 40 Hz 鸣叫声引起的听觉稳态反应 (ASSR)。我们计算了诱发 ASSR 的峰峰值幅度 (PPA) 和事件相关频谱扰动 (ERSP)，并观察到积极情绪显着增强了大脑对听觉刺激的反应 (p <; 0.001)，但消极情绪中的 ASSR状态与中性状态相比没有明显增强。随后，回归分析显示 PPA 和两个情绪维度的评分之间存在显着的正多重线性关系，表明唤醒和效价共同调节听觉皮层的同步振荡，而不是孤立的效价，这有可能澄清围绕负面情绪在听觉反应中的作用。因为在现实生活中抑郁症一般表现为低唤醒度、低效价，而在实验室条件下诱发的负面情绪却总是低效价、高唤醒度。