Abstract

Background

Nearly half of adults with human immunodeficiency virus (HIV) experience HIV-Associated Neurocognitive Disorder (HAND), characterized by cognitive impairments in two or more cognitive domains, which can interfere with everyday functioning. Many factors are thought to influence such cognitive impairments in adults with HIV; one factor seldom examined is personality.

Objective

This study investigated the association between five major dimensions of personality (openness, conscientiousness, extraversion, agreeableness, and neuroticism) and cognitive function in older adults with HIV.

Methods

In this cross-sectional study, a secondary data analysis was conducted on 261 HIV + participants. Participants completed a norm-based cognitive battery covering seven cognitive domains, which yielded the following indices: global cognitive impairment, and global and domain-specific T-scores. The Big Five Inventory was used to assess personality traits.

Results

Higher openness, conscientiousness, and agreeableness were associated with better performance on individual cognitive domains while agreeableness and openness were also positively associated with global cognitive T-scores (p < .01). Only openness significantly predicted global cognition when adjusting for covariates (p < .01).

Discussion

Openness was associated with better global cognitive function in persons with HIV. This study provides a basis for further investigation of potential mechanisms for the association between personality and cognition in people with HIV in order to ultimately inform intervention strategies.

中文翻译：

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感染人类免疫缺陷病毒（HIV）的中老年人人格与认知表现之间的关系

 抽象的

 背景

近一半感染人类免疫缺陷病毒 (HIV) 的成年人患有 HIV 相关神经认知障碍 (HAND)，其特征是两个或多个认知领域出现认知障碍，这可能会干扰日常功能。许多因素被认为会影响成人艾滋病毒感染者的认知障碍。很少被考察的因素之一是个性。

 客观的

这项研究调查了老年艾滋病毒感染者的五个主要人格维度（开放性、尽责性、外向性、宜人性和神经质）与认知功能之间的关联。

 方法

在这项横断面研究中，对 261 名 HIV + 参与者进行了二次数据分析。参与者完成了涵盖七个认知领域的基于规范的认知电池，产生了以下指数：整体认知障碍以及整体和特定领域的 T 分数。大五量表用于评估人格特质。

 结果

较高的开放性、尽责性和宜人性与个人认知领域的更好表现相关，而宜人性和开放性也与整体认知 T 分数正相关 ( p < .01)。在调整协变量时，只有开放性才能显着预测全局认知 ( p < .01)。

 讨论

开放性与艾滋病毒感染者更好的整体认知功能相关。这项研究为进一步研究艾滋病毒感染者人格与认知之间关联的潜在机制提供了基础，以便最终为干预策略提供信息。