Lentibacillus species are gram variable aerobic bacteria that live primarily in halophilic environments. Previous reports have shown that bacteria belonging to this species are primarily isolated from salty environments or food. We isolated a bacterial strain CBA3610, identified as a novel species of the genus Lentibacillus, from a human fecal sample. In this report, the whole genome sequence of Lentibacillus sp. CBA3610 is presented, and genomic analyses are performed. Complete genome sequence of strain CBA3610 was obtained through PacBio RSII and Illumina HiSeq platforms. The size of genome is 4,035,571 bp and genes estimated to be 4714 coding DNA sequences and 64 tRNA and 17 rRNA were identified. The phylogenetic analysis confirmed that it belongs to the genus Lentibacillus. In addition, there were genes related to antibiotic resistance and virulence, and genes predicted as CRISPR and prophage were also identified. Genes related to osmotic stress were found according to the characteristics of halophilic bacterium. Genomic differences from other Lentibacillus species were also confirmed through comparative genomic analysis. Strain CBA3610 is predicted to be a novel candidate species of Lentibacillus through phylogenetic analysis and comparative genomic analysis with other species in the same genus. This strain has antibiotic resistance gene and pathogenic genes. In future, the information derived from the results of several genomic analyses of this strain is thought to be helpful in identifying the relationship between halophilic bacteria and human gut microbiota.

中文翻译：

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嗜盐细菌Lentibacillus sp. 的基因组分析。CBA3610，来源于人类粪便

慢杆菌属是革兰氏变异需氧细菌，主要生活在嗜盐环境中。先前的报告表明，属于该物种的细菌主要是从咸环境或食物中分离出来的。我们从人类粪便样本中分离出细菌菌株 CBA3610，该菌株被鉴定为 Lentibacillus 属的新物种。在本报告中，Lentibacillus sp. 的全基因组序列。介绍了 CBA3610，并进行了基因组分析。通过PacBio RSII和Illumina HiSeq平台获得菌株CBA3610的完整基因组序列。基因组大小为 4,035,571 bp，估计基因为 4714 个编码 DNA 序列和 64 个 tRNA 和 17 个 rRNA。系统发育分析证实它属于Lentibacillus属。此外，存在与抗生素抗性和毒力相关的基因，还鉴定了预测为 CRISPR 和原噬菌体的基因。根据嗜盐菌的特性，发现与渗透胁迫相关的基因。通过比较基因组分析也证实了与其他慢杆菌属物种的基因组差异。通过系统发育分析和与同属其他物种的比较基因组分析，菌株CBA3610被预测为Lentibacillus的新候选物种。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。并且还鉴定了预测为 CRISPR 和原噬菌体的基因。根据嗜盐菌的特性，发现与渗透胁迫相关的基因。通过比较基因组分析也证实了与其他慢杆菌属物种的基因组差异。通过系统发育分析和与同属其他物种的比较基因组分析，菌株CBA3610被预测为Lentibacillus的新候选物种。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。并且还鉴定了预测为 CRISPR 和原噬菌体的基因。根据嗜盐菌的特性，发现与渗透胁迫相关的基因。通过比较基因组分析也证实了与其他慢杆菌属物种的基因组差异。通过系统发育分析和与同属其他物种的比较基因组分析，菌株CBA3610被预测为Lentibacillus的新候选物种。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。通过比较基因组分析也证实了与其他慢杆菌属物种的基因组差异。通过系统发育分析和与同属其他物种的比较基因组分析，菌株CBA3610被预测为Lentibacillus的新候选物种。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。通过比较基因组分析也证实了与其他慢杆菌属物种的基因组差异。通过系统发育分析和与同属其他物种的比较基因组分析，菌株CBA3610被预测为Lentibacillus的新候选物种。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。该菌株具有抗生素抗性基因和致病基因。未来，从该菌株的几个基因组分析结果中获得的信息被认为有助于确定嗜盐细菌与人类肠道微生物群之间的关系。