Objectives To understand variability in modified Rankin Scale scores from discharge to 90 days in acute ischaemic stroke patients following treatment, and examine prediction of 90-day modified Rankin Scale score by using discharge modified Rankin Scale and discharge disposition. Materials and methods Retrospective analysis of acute ischaemic stroke patients following treatment was performed from January 2016 to March 2020. Data collection included demographic and clinical characteristics and outcomes data (modified Rankin Scale score at discharge, 30 days and 90 days and discharge disposition). Pearson’s χ2 test assessed statistical differences in distribution of modified Rankin Scale scores at discharge, 30 days and 90 days. The predictive power of discharge modified Rankin Scale score and disposition quantified the association with 90-day outcome. Results A total of 280 acute ischaemic stroke patients (65.4% aged ≥65 years, 47.1% female, 60.7% white) were included in the analysis. The modified Rankin Scale score significantly changed between 30 and 90 days from discharge (p<0.001) after remaining stable from discharge to 30 days (p=0.665). The positive and negative predictive values of an unfavourable long-term outcome for discharge modified Rankin Scale scores of 3–5 were 67.7% (95% CI 60.4% to 75.0%) and 82.0% (95% CI 75.1% to 88.8%), and for non-home discharge disposition were 72.4% (95% CI 64.5% to 80.2%) and 74.5% (95% CI 67.8% to 81.3%), respectively. Conclusions Discharge modified Rankin Scale score and non-home discharge disposition are good individual predictors of 90-day modified Rankin Scale score for ischaemic stroke patients following treatment. The data that support the findings of this study are available from the corresponding author on reasonable request.

中文翻译：

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利用出院信息预测急性缺血性卒中患者治疗后 90 天改良 Rankin 量表评分


目的 了解急性缺血性脑卒中患者从出院到治疗后 90 天改良 Rankin 量表评分的变异性，并使用出院改良 Rankin 量表和出院处置检查对 90 天改良 Rankin 量表评分的预测。材料和方法对2016年1月至2020年3月治疗后的急性缺血性卒中患者进行回顾性分析。数据收集包括人口统计学和临床​​特征以及结果数据（出院时、30天和90天的改良Rankin量表评分以及出院处置）。 Pearson χ2 检验评估了出院时、30 天和 90 天改良Rankin 量表评分分布的统计差异。出院修正兰金量表评分和处置的预测能力量化了与 90 天结果的关联。结果 共有280名急性缺血性脑卒中患者（65.4%年龄≥65岁，47.1%女性，60.7%白人）纳入分析。出院后 30 天（p=0.665）保持稳定后，改良Rankin量表评分在出院后 30 至 90 天之间发生显着变化（p<0.001）。出院改良Rankin量表评分3-5分的不良长期结果的阳性和阴性预测值分别为67.7%（95% CI 60.4%至75.0%）和82.0%（95% CI 75.1%至88.8%），和非家庭出院处置分别为 72.4%（95% CI 64.5% 至 80.2%）和 74.5%（95% CI 67.8% 至 81.3%）。结论 出院改良Rankin量表评分和非家庭出院处置是缺血性卒中患者治疗后90天改良Rankin量表评分的良好个体预测因子。 支持本研究结果的数据可根据合理要求从通讯作者处获得。