The aim of this study is to analyze the long-term quality of life after surgery of cavernoma. A monocentric retrospective study was conducted on 69 patients with cavernoma treated microsurgically between 2000 and 2016. The eloquence was adopted from Spetzler-Martin definition. A most recent follow-up was elicited between 2017 and 2019, in which the quality of life (QoL) was evaluated with the Short Form-12 questionnaire (SF12). Forty-one lesions were in eloquent group (EG), 22 in non-eloquent group (NEG), 3 in orbit, and 3 in the spinal cord. Postoperative worsening of the modified Rankin scale (mRS) occurred in 19.5% of cases in EG versus 4.5% in NEG. After a mean follow-up of 6.5 years (SD 4.6), the neurological status was better or unchanged compared to baseline in 85.4% of EG and 100% of NEG. Regarding QoL assessment of 44 patients (EG n = 27, NEG n = 14) attended the last follow-up. Patients after eloquent cavernoma resection reported a non-inferior QoL in most SF12 domains (except for physical role) compared to NEG. However, they reported general health perception inferior to norms, which was affected by the limited physical and emotional roles. At a late follow-up, the surgical morbidity was transient in the NEG and mostly recovered in the EG. The QoL comparison between eloquent and non-eloquent cavernomas created interesting and new data after prolonged follow-up. These results add value for decision-making as well as patient counseling for future encountered cases. Preoperative evaluation of QoL is recommended for future studies to assess QoL dynamics.

本研究的目的是分析海绵状血管瘤手术后的长期生活质量。对 2000 年至 2016 年间接受显微手术治疗的 69 名海绵状血管瘤患者进行了单中心回顾性研究。口才采用了 Spetzler-Martin 定义。最近一次随访是在 2017 年至 2019 年期间进行的，其中使用 Short Form-12 问卷 (SF12) 评估了生活质量 (QoL)。口才组（EG）41个病变，非口才组（NEG）22个，眼眶3个，脊髓3个。改良 Rankin 量表 (mRS) 的术后恶化发生在 EG 的 19.5% 和 NEG 的 4.5%。平均随访 6.5 年 (SD 4.6) 后，85.4% 的 EG 和 100% 的 NEG 的神经状态与基线相比更好或没有变化。关于 44 名患者的生活质量评估（EGn  = 27，NEG n  = 14）参加了最后一次随访。与 NEG 相比，雄辩的海绵状血管瘤切除术后患者报告的大多数 SF12 领域（除了身体作用）的 QoL 不差。然而，他们报告说，一般健康感知低于标准，这受到有限的身体和情感角色的影响。在后期随访中，手术并发症在 NEG 中是短暂的，大部分在 EG 中恢复。经过长时间的随访，雄辩和非雄辩海绵状血管瘤之间的生活质量比较创造了有趣的新数据。这些结果为决策制定以及为未来遇到的病例提供患者咨询增加了价值。建议对 QoL 进行术前评估以用于未来的研究以评估 QoL 动态。