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Nonhuman primate models for SARS-CoV-2 Research: Managing demand for specific-pathogen-free (SPF) animals
Lab Animal ( IF 5.9 ) Pub Date : 2021-06-23 , DOI: 10.1038/s41684-021-00810-2
Miguel A Contreras 1 , Matthew E Arnegard 1 , Michael C Chang 1 , Sheri Hild 1 , Franziska Grieder 1 , Stephanie J Murphy 1
Affiliation  

The SARS-CoV-2/COVID-19 pandemic has significantly increased the demand for specific-pathogen-free (SPF) nonhuman primates (NHPs) for development of vaccines and therapeutics, thus straining the supply of these animals for biomedical research studies. Non-SPF animals, which are available in greater numbers and include well-characterized primate species, should be considered in lieu of limited SPF animals for appropriate research studies.

中文翻译:

用于 SARS-CoV-2 研究的非人类灵长类动物模型:管理对无特定病原体 (SPF) 动物的需求

SARS-CoV-2/COVID-19 大流行显着增加了对用于开发疫苗和治疗剂的无特定病原体 (SPF) 非人类灵长类动物 (NHP) 的需求,从而使这些动物用于生物医学研究的供应紧张。非 SPF 动物数量较多,包括特征明确的灵长类动物,应考虑代替有限的 SPF 动物进行适当的研究。
更新日期:2021-06-24
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