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Evaluation of the Clinical and Laboratory Findings of Asthmatic Children with SARS-CoV-2 Infection
International Archives of Allergy and Immunology ( IF 2.5 ) Pub Date : 2021-06-24 , DOI: 10.1159/000517153 Azize Pınar Metbulut 1 , Özlem Mustafaoğlu 2 , Gülşah Şen 1 , Saliha Kanık Yüksek 2 , İlknur Külhaş Çelik 1 , Halise Akça 3 , Emine Dibek Mısırlıoğlu 1
International Archives of Allergy and Immunology ( IF 2.5 ) Pub Date : 2021-06-24 , DOI: 10.1159/000517153 Azize Pınar Metbulut 1 , Özlem Mustafaoğlu 2 , Gülşah Şen 1 , Saliha Kanık Yüksek 2 , İlknur Külhaş Çelik 1 , Halise Akça 3 , Emine Dibek Mısırlıoğlu 1
Affiliation
Introduction: There are a limited number of studies about the clinical findings of coronavirus infection in pediatric patients with asthma. We aimed to evaluate the clinical and laboratory characteristics of pediatric patients with asthma and healthy children without chronic disease who infected with SARS-CoV-2. Methods: This is a retrospective, case-control study comparing the asthma diagnosed and healthy children who were diagnosed as COVID-19 in our hospital between March 11 and November 10, 2020. Results: During the study period, 6,205 children were diagnosed with COVID-19 in our hospital. Only 54 (0.87%) patients had a diagnosis of asthma. The mean of the age was 10.5 years and 53.7% (n:29) of the patients with asthma were male. Cough, shortness of breath, emesis, and diarrhea were found to be significantly higher in asthma group than in the control group (respectively p = 0.002, 0.000, 0.002, 0.019, 0.015). Patients who were given SABA was significantly higher in asthma diagnosed patients (p = 0.000). Hospitalization was significantly higher in asthma group (p = 0.025), and the duration of hospitalization was significantly higher in control group (p = 0.034). There was no significant difference between the 2 groups in terms of requiring oxygen treatment and in laboratory findings between groups. Conclusion: This study revealed that pediatric patients diagnosed with asthma were in a mild clinic. According to these findings, asthma may not affect the course of the COVID-19 in children.
Int Arch Allergy Immunol
中文翻译：
SARS-CoV-2 感染哮喘儿童的临床和实验室检查结果评估
简介：关于儿科哮喘患者冠状病毒感染的临床结果的研究数量有限。我们的目的是评估感染 SARS-CoV-2 的哮喘儿科患者和无慢性病的健康儿童的临床和实验室特征。方法：这是一项回顾性病例对照研究，比较了 2020 年 3 月 11 日至 11 月 10 日期间在我院确诊的哮喘儿童和被诊断为 COVID-19 的健康儿童。结果：在研究期间，有 6,205 名儿童被诊断为 COVID-19 -19 在我们医院。只有 54 名（0.87%）患者被诊断为哮喘。哮喘患者的平均年龄为 10.5 岁，53.7% ( n :29) 为男性。哮喘组的咳嗽、气短、呕吐和腹泻明显高于对照组（分别p = 0.002、0.000、0.002、0.019、0.015）。接受 SABA 治疗的患者在哮喘诊断患者中的比例显着较高 ( p = 0.000)。哮喘组的住院率显着较高（ p = 0.025），对照组的住院时间显着较高（ p = 0.034）。两组之间在需要氧气治疗和实验室检查结果方面没有显着差异。结论：本研究显示，诊断为哮喘的儿科患者属于轻症门诊。根据这些发现，哮喘可能不会影响儿童 COVID-19 的病程。
Int Arch 过敏免疫
更新日期：2021-06-24
Int Arch Allergy Immunol
中文翻译：
SARS-CoV-2 感染哮喘儿童的临床和实验室检查结果评估
简介：关于儿科哮喘患者冠状病毒感染的临床结果的研究数量有限。我们的目的是评估感染 SARS-CoV-2 的哮喘儿科患者和无慢性病的健康儿童的临床和实验室特征。方法：这是一项回顾性病例对照研究，比较了 2020 年 3 月 11 日至 11 月 10 日期间在我院确诊的哮喘儿童和被诊断为 COVID-19 的健康儿童。结果：在研究期间，有 6,205 名儿童被诊断为 COVID-19 -19 在我们医院。只有 54 名（0.87%）患者被诊断为哮喘。哮喘患者的平均年龄为 10.5 岁，53.7% ( n :29) 为男性。哮喘组的咳嗽、气短、呕吐和腹泻明显高于对照组（分别p = 0.002、0.000、0.002、0.019、0.015）。接受 SABA 治疗的患者在哮喘诊断患者中的比例显着较高 ( p = 0.000)。哮喘组的住院率显着较高（ p = 0.025），对照组的住院时间显着较高（ p = 0.034）。两组之间在需要氧气治疗和实验室检查结果方面没有显着差异。结论：本研究显示，诊断为哮喘的儿科患者属于轻症门诊。根据这些发现，哮喘可能不会影响儿童 COVID-19 的病程。
Int Arch 过敏免疫
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