We aimed to compare accelerated post-contrast magnetization-prepared rapid gradient-echo (MPRAGE) using wave-controlled aliasing in parallel imaging (wave-CAIPI) with conventional MPRAGE as a reliable method to diagnose intracranial lesions in pediatric patients. A total of 23 consecutive pediatric patients who underwent post-contrast wave-CAIPI and conventional MPRAGE (scan time: 2 min 39 s vs. 5 min 46 s) were retrospectively evaluated. Two radiologists independently assessed each image for the presence of intracranial lesions. Quantitative [contrast-to-noise ratio (CNR), contrast rate (CR), and signal-to-noise ratio (SNR)] and qualitative parameters (overall image quality, gray-white matter differentiation, demarcation of basal ganglia and sulci, and motion artifacts) were also surveyed. Wave-CAIPI MPRAGE and conventional MPRAGE detected enhancing and non-enhancing intracranial lesions with 100% agreement. Although wave-CAIPI MPRAGE had a lower SNR (all p < 0.05) and overall image quality (overall analysis, p = 0.02) compared to conventional MPRAGE, other quantitative (CNR and CR) and qualitative parameters (gray-white differentiation, demarcation of basal ganglia and sulci, and motion artifacts) were comparable in the pooled analysis and between both observers (all p > 0.05). Wave-CAIPI MPRAGE was a reliable method for diagnosing intracranial lesions in pediatric patients as conventional MPRAGE at half the scan time.

我们的目的是比较使用平行成像中波控制混叠 (wave-CAIPI) 的加速对比后磁化准备快速梯度回波 (MPRAGE) 与传统 MPRAGE 作为诊断儿科患者颅内病变的可靠方法。回顾性评估了总共 23 名连续接受造影后波 CAIPI 和常规 MPRAGE（扫描时间：2 分 39 秒与 5 分 46 秒）的儿科患者。两名放射科医生独立评估每张图像是否存在颅内病变。定量 [对比度 (CNR)、对比度 (CR) 和信噪比 (SNR)] 和定性参数（整体图像质量、灰白质分化、基底神经节和脑沟的分界、和运动伪影）也进行了调查。Wave-CAIPI MPRAGE 和常规 MPRAGE 检测到增强和非增强颅内病变的一致性为 100%。尽管 wave-CAIPI MPRAGE 具有较低的 SNR（所有p  < 0.05）和整体图像质量（总体分析，p  = 0.02）与传统 MPRAGE 相比，其他定量（CNR 和 CR）和定性参数（灰白分化、基底神经节和脑沟的分界以及运动伪影）具有可比性在汇总分析中以及在两个观察者之间（所有p  > 0.05）。Wave-CAIPI MPRAGE 是诊断儿科患者颅内病变的可靠方法，与传统 MPRAGE 的扫描时间相同。