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Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
Scientific Reports ( IF 4.6 ) Pub Date : 2021-06-24 , DOI: 10.1038/s41598-021-92618-w
Yuan-Chun Huang, Pei-Tseng Kung, Shang-Yun Ho, Yeu-Sheng Tyan, Li-Ting Chiu, Wen-Chen Tsai

Oesophageal cancer is the sixth leading cause of cancer death worldwide. This nationwide study analyses the survival results of oesophageal cancer under multidisciplinary team (MDT) care. We enrolled oesophageal cancer patients diagnosed between 2010 and 2015 with follow-up for at least 1 year. This study performed propensity score matching with a ratio of 1:1 between MDT participants and non-MDT participants. We performed conditional Cox proportional hazards model to research relative risk of survival and associated factors of survival. The adjusted survival curves were plotted. 8184 newly diagnosed oesophageal cancer patients were included. The favourable survival factors include participant status of MDT, gender, monthly salary, urbanization level, other catastrophic illness, stage of cancer, treatment methods, and service volume of physicians (P < 0.05). MDT participants showed lower risk of death (HR = 0.73; 95% CI 0.67–0.79). Further stratification analysis revealed that the incorporation of an MDT reduced the death risk of patients with stages 2, 3, and 4 cancer, with the greatest reduction observed in patients with stage 3 cancer (HR = 0.72; 95% CI 0.67–0.79). The risk of death was lower for oesophageal cancer patients who enrolled in MDT care.



中文翻译:

多学科团队护理对食管癌患者生存率的影响:一项回顾性全国队列研究

食道癌是全球第六大癌症死亡原因。这项全国性研究分析了多学科团队 (MDT) 护理下食管癌的生存结果。我们招募了 2010 年至 2015 年间诊断出的食管癌患者,随访时间至少为 1 年。本研究进行了倾向评分匹配,MDT 参与者和非 MDT 参与者之间的比例为 1:1。我们进行了条件 Cox 比例风险模型来研究生存的相对风险和相关的生存因素。绘制了调整后的生存曲线。纳入8184例初诊食管癌患者。有利生存因素包括MDT的参与者状况、性别、月薪、城市化水平、其他灾难性疾病、癌症分期、治疗方法和医生的服务量。P  < 0.05)。MDT 参与者的死亡风险较低(HR = 0.73;95% CI 0.67–0.79)。进一步的分层分析显示,合并 MDT 降低了 2、3 和 4 期癌症患者的死亡风险,在 3 期癌症患者中观察到的降低幅度最大(HR = 0.72;95% CI 0.67–0.79)。参加 MDT 治疗的食管癌患者的死亡风险较低。

更新日期:2021-06-24
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