Autonomic Neuroscience ( IF 3.2 ) Pub Date : 2021-06-24 , DOI: 10.1016/j.autneu.2021.102837 Michael Duffy 1 , Jack Garland 2 , Benjamin Ondruschka 3 , Julian F R Paton 4 , Emma N Bardsley 4 , Christopher X Wong 5 , Simon Stables 6 , Rexson Tse 6
Sudden cardiac death (SCD) is the most common natural cause of death. The hypothesized mechanism of death is an arrhythmia precipitated by increased sympathetic outflow. The left stellate ganglion provides sympathetic innervation to the heart and plays a role in arrhythmogensis. We present a SCD with stellate ganglionitis in which the inflammatory cells were characterized. The case was 37-year-old man who died from ischemic and hypertensive heart disease. The left stellate ganglion showed lymphocytic inflammation with features of humoral immune response. This case report provides evidence that stellate ganglionitis can be seen in SCD and raises the possible association between the two.
中文翻译:
心源性猝死中的星状神经节炎:病例报告
心源性猝死 (SCD) 是最常见的自然死亡原因。假设的死亡机制是交感神经流出增加引起的心律失常。左星状神经节为心脏提供交感神经支配并在心律失常中起作用。我们提出了星状神经节炎的 SCD,其中炎症细胞为特征。该病例为 37 岁男性,死于缺血性和高血压性心脏病。左侧星状神经节表现为淋巴细胞性炎症,具有体液免疫反应特征。本病例报告提供的证据表明星状神经节炎可见于 SCD,并提出了两者之间可能的关联。