Kleine-Levin syndrome (KLS) is a rare disorder of recurrent hypersomnolence. The pathophysiology continues to be poorly understood. Autoimmunity, genetic polymorphisms, dysfunction of the hypothalamic axis, and abnormalities in functional imaging have been proposed. Several triggers have been described, including infection, toxins, head trauma, sleep deprivation, lactation, and menses. We present the first case report in the medical literature of KLS triggered by pregnancy and the first KLS from Armenia. Our patient has a pattern of mostly pregnancy-related episodes of several day sleepiness occurring monthly. This case adds to the published literature as we present a new association and explore the pathophysiology of KLS.

Kleine-Levin 综合征 (KLS) 是一种罕见的反复嗜睡症。病理生理学仍然知之甚少。已经提出了自身免疫、遗传多态性、下丘脑轴功能障碍和功能成像异常。已经描述了几种触发因素，包括感染、毒素、头部创伤、睡眠剥夺、哺乳和月经。我们在医学文献中介绍了第一个由妊娠引发的 KLS 病例报告和来自亚美尼亚的第一个 KLS。我们的患者的模式主要是与妊娠相关的数日嗜睡发作，每月发生一次。这个案例增加了已发表的文献，因为我们提出了一个新的关联并探索了 KLS 的病理生理学。