Whereas initial findings have already identified cortical patterns accompanying proprioceptive deficiencies in patients after anterior cruciate ligament reconstruction, little is known about compensatory sensorimotor mechanisms for re-establishing postural control. Therefore, the aim of the present study was to explore leg dependent patterns of cortical contributions to postural control in patients six weeks following anterior cruciate ligament reconstruction. A total of 12 patients after anterior cruciate ligament reconstruction (25.1 ± 3.2 years, 178.1 ± 9.7 cm, 77.5 ± 14.4 kg) and another 12 gender, age and activity matched healthy controls participated in this study. All subjects performed 10 x 30 sec. single leg stances on each leg, equipped with 64-channel mobile electroencephalography. Postural stability was quantified by area of sway and sway velocity. Estimations of the weighted phase lag index were conducted as a cortical measure of functional connectivity. The findings showed significant group × leg interactions for increased functional connectivity in the ACL injured leg, predominantly including fronto‐parietal (F(1, 22) = 8.41, p ≤ .008, η2 = .28), fronto‐occipital (F(1, 22) = 4.43, p ≤ .047, η2 = .17), parieto‐motor (F(1, 22) = 10.30, p ≤ .004, η2 = .32), occipito‐motor (F(1, 22) = 5.21, p ≤ .032, η2 = .19) and occipito‐parietal (F(1, 22) = 4.60, p ≤ .043, η2 = .17) intra‐hemispherical connections in the contralateral hemisphere and occipito‐motor (F(1, 22) = 7.33, p ≤ .013, η2 = .25) on the ipsilateral hemisphere to the injured leg. Higher functional connectivity in patients after anterior cruciate ligament reconstruction, attained by increased emphasis of functional connections incorporating the somatosensory and visual areas, may serve as a compensatory mechanism to control postural stability of the injured leg in the early phase of rehabilitation. These preliminary results may help to develop new neurophysiological assessments for detecting functional deficiencies after anterior cruciate ligament reconstruction in the future.

中文翻译：

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前交叉韧带重建后六周患者与姿势控制相关的功能性皮质连接

尽管最初的研究结果已经确定了前交叉韧带重建后患者伴随本体感觉缺陷的皮质模式，但对重新建立姿势控制的补偿性感觉运动机制知之甚少。因此，本研究的目的是探索前交叉韧带重建后六周患者的皮质对姿势控制的贡献的腿部依赖性模式。共有12名前交叉韧带重建患者（25.1±3.2岁，178.1±9.7厘米，77.5±14.4公斤）和另外12名性别、年龄和活动匹配的健康对照参加了本研究。所有受试者进行 10 x 30 秒。每条腿单腿站立，配备64通道移动脑电图仪。姿势稳定性通过摇摆面积和摇摆速度来量化。加权相位滞后指数的估计是作为功能连接的皮质测量进行的。研究结果显示，ACL 受伤腿的功能连接性增加显着的组×腿相互作用，主要包括额顶叶 (F(1, 22) = 8.41, p ≤ .008, η2 = .28)、额枕叶 (F( 1, 22) = 4.43, p ≤ .047, η2 = .17), 顶运动 (F(1, 22) = 10.30, p ≤ .004, η2 = .32), 枕运动 (F(1, 22) = 5.21, p ≤ .032, η2 = .19) 和枕顶叶 (F(1, 22) = 4.60, p ≤ .043, η2 = .17) 对侧半球和枕骨的半球内连接运动 (F(1, 22) = 7.33, p ≤ .013, η2 = .25) 在受伤腿的同侧半球上。前交叉韧带重建后患者的更高功能连接，通过增加结合体感和视觉区域的功能连接获得，可以作为一种补偿机制，在康复的早期控制受伤腿的姿势稳定性。这些初步结果可能有助于开发新的神经生理学评估，以检测未来前交叉韧带重建后的功能缺陷。