Highly electroactive transition metal oxides have been received great potential in antibiotic drug electrochemical sensors due to excellent features including ease of preparation, a large number of active sites, good conductivity, high stability, and selectivity. In this work, the perovskite-type silver titanate (Ag₂TiO₃) was synthesized by ultrasound-assisted coprecipitation method. The structural and morphology were examined using typical analytical techniques such as X-ray diffraction (XRD) Fourier transform infrared spectroscopy (FT-IR), Raman spectrometry, field-emission scanning electron microscope (FE-SEM), transmission electron microscope (TEM), and X-ray photoelectron spectroscopy (XPS) analyzes confirmed the purity and the chemical composition of as-prepared Ag₂TiO₃. The Brunauer−Emmett−Teller analysis (BET) of as-synthesized Ag₂TiO₃ displayed a specific surface area of 48.485 m² g⁻¹ resulted in improved charge transfer resistance (R_ct) of 695 Ω. The cyclic voltammetry (CV) analysis revealed the superior electrochemical performance of Ag₂TiO₃ than other electrodes towards metronidazole (MTZ) detection. Under optimized differential pulse voltammetric (DPV) studies, the modified electrode exhibits a wide linear range of 0.1–104.3 μM with the lowest detection limit of 0.011 μM and a sensitivity of 0.371 μA μM⁻¹ cm⁻². Furthermore, the fabricated sensor displayed excellent cyclic stability, reproducibility, repeatability, and noticeable selectivity in potentially effective interfering compounds for the detection of MTZ. The constructed electrode delivered good sensitivity to MTZ in urine and tablet with acceptable recoveries.

高电活性过渡金属氧化物由于具有制备容易、活性位点多、导电性好、稳定性高和选择性好等优点，在抗生素药物电化学传感器中具有巨大的潜力。在这项工作中，钙钛矿型钛酸银（Ag₂TiO₃）是通过超声辅助共沉淀法合成的。使用典型的分析技术，如 X 射线衍射 (XRD) 傅立叶变换红外光谱 (FT-IR)、拉曼光谱、场发射扫描电子显微镜 (FE-SEM)、透射电子显微镜 (TEM) 和 X 射线光电子能谱 (XPS) 分析证实了所制备的 Ag ₂ TiO ₃的纯度和化学成分。合成后的Ag ₂ TiO ₃的Brunauer-Emmett-Teller 分析(BET)显示48.485 m ²  g ^-1的比表面积导致695 Ω 的改进的电荷转移电阻(R _ct )。循环伏安法 (CV) 分析揭示了Ag ₂ TiO ₃优异的电化学性能比其他电极用于甲硝唑 (MTZ) 检测。在优化的差分脉冲伏安 (DPV) 研究下，修饰电极表现出 0.1–104.3 μM 的宽线性范围，最低检测限为 0.011 μM，灵敏度为 0.371 μA μM ^-1 cm ^-2。此外，制造的传感器在用于检测 MTZ 的潜在有效干扰化合物中显示出优异的循环稳定性、再现性、可重复性和显着的选择性。构建的电极对尿液和片剂中的 MTZ 具有良好的灵敏度，回收率可接受。