: Bisphosphonates are increasingly recognized for their anti-neoplastic properties, which are the result of their action on the mevalonate pathway. Our primary aim was to investigate the association between bisphosphonate use and survival in patients with pancreatic cancer. Since statins also act on the mevalonate pathway, we also investigated the effect of the combined use of bisphosphonates and statins on survival.

中文翻译：

---

双膦酸盐的使用不影响胰腺癌患者的生存期：倾向评分匹配分析。

：双膦酸盐因其抗肿瘤特性而得到越来越多的认可，这是它们对甲羟戊酸途径作用的结果。我们的主要目的是研究双膦酸盐的使用与胰腺癌患者生存率之间的关联。由于他汀类药物也作用于甲羟戊酸途径，我们还研究了双膦酸盐和他汀类药物联合使用对存活率的影响。