Orthodox theology teaches that people may participate in the fruits of Jesus Christ’s mediation between God and humankind. The Holy Spirit enables people to become radiant with the divine energies as they embrace Christ’s fulfillment of the human person in the likeness of God. The Theotokos, the saints, and spiritual elders play particular roles in interceding for people to share more fully in the life of Christ. The eucharistic worship of the church, marriage and the other sacraments, the prayer of the heart, ministry to the poor, and forgiveness of enemies provide opportunities for people to be transformed by the grace mediated to humanity by Jesus Christ. Such mediation extends to every dimension of the human person, including the physical body, as indicated by veneration of the relics of the saints and the sacramental nature of Orthodox worship.

东正教神学教导人们可以参与耶稣基督在上帝与人类之间调解的成果。当人们拥抱基督在上帝的样式中实现人性时，圣灵使他们能够散发出神圣的能量。在东正、圣徒和属灵长老在代求人们更充分地分享基督的生活方面发挥着特殊的作用。教会的圣体崇拜、婚姻和其他圣礼、心灵的祈祷、对穷人的事工和对敌人的宽恕，为人们提供了机会，让人们通过耶稣基督为人类提供的恩典而改变。这种调解延伸到人的各个方面，包括身体，正如对圣人遗物的崇敬和东正教崇拜的圣事性质所表明的那样。