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Bile pulmonary embolism-related sudden death following an abdominal firearm injury: An autopsy case report and review of literature
Forensic Science, Medicine and Pathology ( IF 1.5 ) Pub Date : 2021-06-23 , DOI: 10.1007/s12024-021-00394-w
Nora Fawzy Fnon , Hamed Mahmoud Seleim , Mohammed Shabana Abdel-wahab , Zahraa Khalifa Sobh

Bile pulmonary embolism (BPE) is a rare type of non-thrombotic pulmonary embolism (NTPE). For bile emboli to pass through the bloodstream to the lungs, there must be a connection created between the biliary and the venous vessels. This article reports a fatal BPE in a 12-year-old child who died 14 days following an abdominal firearm injury. The right lobe of the liver had a yellowish-green stained lacerated track along with bile collection. Both lungs were congested with peripheral dark areas in all lobes. Microscopically, many interstitial pulmonary arterioles were occluded by bile emboli along with the presence of hemorrhagic infarcts. Other than the present case, only 21 cases of BPE were published in the literature until the present day. The history of hepatic trauma and/or hepatobiliary disease in association with pulmonary manifestations points to BPE as a possible diagnosis. However, visualization of bile emboli within the pulmonary vessels is pathognomonic for BPE.



中文翻译:

腹部火器伤致胆管肺栓塞相关猝死:尸检病例报告及文献复习

胆汁性肺栓塞 (BPE) 是一种罕见的非血栓性肺栓塞 (NTPE)。胆汁栓子要通过血流到达肺部,必须在胆管和静脉血管之间建立连接。本文报告了一名 12 岁儿童的致命 BPE,他在腹部枪支受伤后 14 天死亡。肝脏右叶有一条黄绿色染色的撕裂痕迹,并伴有胆汁积聚。双肺充血,所有肺叶周围都有暗区。在显微镜下,许多间质性肺小动脉被胆汁栓塞阻塞,并伴有出血性梗塞。除本病例外,直到今天,文献中仅发表了 21 例 BPE。与肺部表现相关的肝外伤和/或肝胆疾病史表明 BPE 是一个可能的诊断。然而,肺血管内胆汁栓子的可视化是 BPE 的特征。

更新日期:2021-06-23
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