Daporinad is a novel and potent inhibitor of nicotinamide phosphoribosyl transferase with potential antineoplastic and antiangiogenic activities. We aimed to explore the metabolites of daporinad generated from liver microsomes and to propose metabolic pathways.

中文翻译：

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通过液相色谱/四极杆-轨道阱质谱法通过大鼠、狗、猴和人肝微粒体对 Daporinad 进行体外代谢物分析

Daporinad 是一种新型有效的烟酰胺磷酸核糖转移酶抑制剂，具有潜在的抗肿瘤和抗血管生成活性。我们旨在探索从肝微粒体产生的达泊宁的代谢物并提出代谢途径。