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Use of erythropoietin in ophthalmology: a review
Survey of Ophthalmology ( IF 5.1 ) Pub Date : 2021-06-23 , DOI: 10.1016/j.survophthal.2021.06.002
Sepehr Feizi 1 , Mohammadhasan Alemzadeh-Ansari 1 , Farid Karimian 1 , Hamed Esfandiari 2
Affiliation  

Erythropoietin (EPO) is a glycoprotein hormone that regulates hematopoiesis in the human body. The presence of EPO and its receptors in different tissues indicates that this hormone has extramedullary effects in other tissues, including the eye. We focus on the biological roles of this hormone in the development and normal physiologic functions of the eye. Furthermore, we explore the role of EPO in the management of different ocular diseases – including diabetic retinopathy, retinopathy of prematurity, inherited retinal degeneration, branch and central retinal vein occlusion, retinal detachment, traumatic optic neuropathy, optic neuritis, methanol optic neuropathy, nonarteritic anterior ischemic optic neuropathy, glaucoma, and scleral necrosis.



中文翻译:

促红细胞生成素在眼科中的应用:综述

促红细胞生成素 (EPO) 是一种糖蛋白激素,可调节人体内的造血功能。EPO 及其受体在不同组织中的存在表明这种激素在包括眼睛在内的其他组织中具有髓外作用。我们专注于这种激素在眼睛发育和正常生理功能中的生物学作用。此外,我们探讨了 EPO 在治疗不同眼部疾病中的作用——包括糖尿病性视网膜病变、早产儿视网膜病变、遗传性视网膜变性、视网膜分支和中央静脉阻塞、视网膜脱离、创伤性视神经病变、视神经炎、甲醇视神经病变、非动脉炎前部缺血性视神经病变、青光眼和巩膜坏死。

更新日期:2021-06-23
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