Purpose

To investigate if a lower luminance monochromatic LED stimulus could be used as an alternative to a high luminance white light for the clinical electrooculogram.

Methods

Clinical electrooculograms were recorded in color normal participants (N = 23) aged 22.6 ± 1.2 years, 7 male and 16 female using the standard 100 cd.m⁻² white illuminant and four monochromatic LEDs with peak wavelengths of 448, 534, 596 and 634 nm at 30 cd.m⁻². Pupils were dilated and there was a 30 cd.m⁻²pre-adaptation to white light for 2 min followed by 15 min dark adaptation and 20 min recording in the light stimulus using a Ganzfeld stimulator.

Results

The normalized LP:DTratio for the short wavelength LED (448 nm) was equivalent in amplitude and timing to the ISCEV standard EOG (p = .99). The LP:DTratio for the white (100 cd.m⁻²) and 448 nm (30 cd.m⁻²) were (median ± SEM): 2.49 ± .11 and 2.47 ± .11. The time to light-rise peak was also equivalent being 9.0 ± .2 and 8.0 ± .4 min (p = .54).

Conclusions

Consideration may be given to using a short wavelength monochromatic stimulus that is more comfortable for the subject than the current 100 cd.m⁻² illuminant.

中文翻译：

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白光是临床眼电图的合适光源吗？

目的

研究是否可以使用较低亮度的单色 LED 刺激作为临床眼电图的高亮度白光的替代方案。

方法

 使用标准的 100 cd.m ^-2白色光源和四个峰值波长分别为448、534、596和 634 的单色 LED，记录了年龄为 22.6 ± 1.2 岁的有色正常参与者 ( N = 23)、7 名男性和 16 名女性的临床眼电图nm 在 30 cd.m ^-2。瞳孔扩大，对白光进行30 cd.m ^-2预适应 2 分钟，然后是 15 分钟暗适应，并使用 Ganzfeld 刺激器在光刺激下记录 20 分钟。

结果

短波长 LED (448 nm) 的归一化 LP:DTratio 在幅度和时序上与 ISCEV 标准 EOG ( p  = .99) 相同。白色 (100 cd.m ^-2 ) 和 448 nm (30 cd.m ^-2 )的 LP:DTratio 为（中值 ± SEM）：2.49 ± .11 和 2.47 ± .11。光升峰值的时间也相当于 9.0 ± .2 和 8.0 ± .4 分钟 ( p  = .54)。

结论

可以考虑使用比当前的 100 cd.m ^-2光源对受试者更舒适的短波长单色刺激。