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Protective Effects of Zinc on Spinal Cord Injury
Journal of Molecular Neuroscience ( IF 3.1 ) Pub Date : 2021-06-23 , DOI: 10.1007/s12031-021-01859-x
Shan Wen 1 , Yuanlong Li 1 , Xiaolei Shen 1 , Zhe Wang 1 , Kaihua Zhang 1 , Jiawei Zhang 1 , Xifan Mei 1
Affiliation  

Spinal cord injury is a serious disease of the central nervous system, but there is no effective treatment. And zinc is an essential nutrient for human body and participates in many physiological processes, such as immune response, homeostasis, oxidative stress, cell cycle progression, DNA replication, DNA damage repair, apoptosis, and aging. This article mainly summarizes that zinc could predict the prognosis and treat the spinal cord injury. Especially, zinc could help to inhibit inflammation, regulate autophagy, and reduce oxidative stress. However, excessive zinc will damage neurons.



中文翻译:

锌对脊髓损伤的保护作用

脊髓损伤是一种严重的中枢神经系统疾病,但目前尚无有效的治疗方法。锌是人体必需的营养素,参与免疫反应、体内平衡、氧化应激、细胞周期进程、DNA复制、DNA损伤修复、细胞凋亡和衰老等多种生理过程。本文主要总结锌可以预测预后和治疗脊髓损伤。特别是锌可以帮助抑制炎症,调节自噬,减少氧化应激。然而,过量的锌会损害神经元。

更新日期:2021-06-23
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