Applications of clinical decision support systems (CDSS) have become essential for physicians seeking to make appropriate decisions. The implementation of CDSS, however, is complicated if the factors affecting physician’s acceptance are not recognised. This study aims to explore the various factors that may influence the acceptance of CDSS in Saudi Arabia. A qualitative method was used to collect data from interviews with 54 GPs, with interviews conducted in three stages. The study then integrated the Unified Theory of Acceptance and Use of Technology (UTAUT) and Task-Technology Fit (TTF) models to communicate the findings. It is suggested that all factors of both UTAUT and TTF influence acceptance of CDSS by GPs, with the sole exception of the social influence factor. Some additional factors were also discovered by means of in-depth interviews, including accessibility, patient satisfaction, informativeness (increased knowledge), connectedness (informing patients), communication and shared knowledge, privacy and security, and perceived risk (functional performance risk and time risk). The study thus offers a new insight of the factors influencing GPs’ acceptance of CDSS.

临床决策支持系统 (CDSS) 的应用对于寻求做出适当决策的医生来说已经变得必不可少。但是，如果不认识到影响医生接受度的因素，CDSS 的实施就会变得复杂。本研究旨在探讨可能影响沙特阿拉伯接受 CDSS 的各种因素。使用定性方法从与 54 位全科医生的访谈中收集数据，访谈分三个阶段进行。然后，该研究整合了技术接受和使用统一理论 (UTAUT) 和任务技术拟合 (TTF) 模型来传达研究结果。建议 UTAUT 和 TTF 的所有因素都会影响 GP 对 CDSS 的接受，唯一的例外是社会影响因素。通过深度访谈还发现了一些额外的因素，包括可及性、患者满意度、信息量（增加知识）、连通性（告知患者）、沟通和共享知识、隐私和安全以及感知风险（功能性能风险和时间风险）。因此，该研究为影响全科医生接受 CDSS 的因素提供了新的见解。