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High sensitivity and specificity of a 5-analyte protein and microRNA biosignature for identification of active tuberculosis
Clinical & Translational Immunology ( IF 4.6 ) Pub Date : 2021-06-22 , DOI: 10.1002/cti2.1298
Jessica L Pedersen 1 , Simone E Barry 2, 3 , Nilesh J Bokil 1 , Magda Ellis 2 , YuRong Yang 4 , Guangyu Guan 5 , Xiaolin Wang 4 , Alen Faiz 1 , Warwick J Britton 2 , Bernadette M Saunders 1, 2
Affiliation  

Non-sputum-based tests to accurately identify active tuberculosis (TB) disease and monitor response to therapy are urgently needed. This study examined the biomarker capacity of a panel of plasma proteins alone, and in conjunction with a previously identified miRNA signature, to identify active TB disease.

中文翻译:

5 种分析物蛋白和 microRNA 生物印记的高灵敏度和特异性,用于鉴定活动性结核病

迫切需要基于非痰液的检测来准确识别活动性肺结核 (TB) 疾病并监测对治疗的反应。这项研究单独检查了一组血浆蛋白的生物标志物能力,并结合先前确定的 miRNA 特征来识别活动性结核病。
更新日期:2021-06-23
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