BACKGROUND Premature treatment discontinuation (dropout) is a common problem among patients seeking treatment for major depressive disorder (MDD). To prevent treatment dropout, it is important to identify its associated risk factors. The impact anxiety has on treatment dropout for MDD is especially critical to investigate due to the high rates of comorbidity between anxiety and depressive disorders. Evidence for the degree to which anxiety reliably predicts treatment dropout for MDD remains inconclusive and has yet to be investigated at an adult partial hospitalization program. Examining this can help elucidate which factors predict dropout among patients who need intensive treatment for their depression. METHODS Participants were patients seeking treatment for MDD at an adult partial hospitalization program (N = 461). A series of Chi-square tests and t tests were conducted to assess for any differences in frequencies of anxiety disorder comorbidities or mean scores of dimensional anxiety among patients who dropped out of treatment and those who did not. RESULTS No significant associations between high baseline anxiety and early dropout were found (all P > .05). CONCLUSIONS Findings suggest that no specific actions need to be taken to prevent individuals with high baseline levels of anxiety from prematurely dropping out of a partial hospitalization program.

中文翻译：

---

焦虑对在强化部分住院计划中退出重度抑郁症治疗的影响

背景 过早停止治疗（辍学）是寻求重度抑郁症（MDD）治疗的患者中的常见问题。为了防止治疗辍学，重要的是确定其相关的风险因素。由于焦虑和抑郁症之间的高共病率，焦虑对 MDD 治疗辍学的影响对于调查尤其重要。焦虑可靠地预测 MDD 治疗退出的程度的证据仍然没有定论，尚未在成人部分住院计划中进行调查。检查这一点有助于阐明哪些因素可以预测需要强化治疗的抑郁症患者的辍学。方法参与者是在成人部分住院计划中寻求 MDD 治疗的患者（N = 461）。进行了一系列卡方检验和 t 检验，以评估退出治疗的患者和未退出治疗的患者在焦虑症合并症的频率或维度焦虑的平均分数方面的任何差异。结果 未发现高基线焦虑与早期辍学之间存在显着关联（所有 P > .05）。结论 研究结果表明，不需要采取具体行动来防止具有高基线焦虑水平的个体过早退出部分住院治疗计划。结果 未发现高基线焦虑与早期辍学之间存在显着关联（所有 P > .05）。结论 研究结果表明，无需采取具体行动来防止具有高基线焦虑水平的个体过早退出部分住院治疗计划。结果 未发现高基线焦虑与早期辍学之间存在显着关联（所有 P > .05）。结论 研究结果表明，不需要采取具体行动来防止具有高基线焦虑水平的个体过早退出部分住院治疗计划。