In this work, we have observed change in different physical properties and glucose sensing capability of Chitosan-Silica nanoparticle composite membranes (CSNCM) with pore diameter variation. For a particular mixture percentage of chitosan and SiNp dust, successful fabrication of deformation free, free-standing membrane formation was possible. Silica nanoparticles of three different sizes (NP1 ~ 100 nm, NP2 ~ 300 nm & NP3 ~ 500 nm) were prepared to produce CSNCM of corresponding pore sizes (CM1, CM2 and CM3 respectively). Hot NaOH etching was performed to induce surface pore in CSNCM matrix by dissolving Silica nanoparticles from the top layer. We have found that pore distribution, surface morphology, optical properties and dielectric properties are very much dependent on pore size of the membranes. For glucose sensing characterization, we have focussed on multi-parametric optical sensitivity of the membranes in presence of glucose molecules and found that, though all three membranes show response in one or more parameters, only CM2 membranes hold the capability to perform as a multi-parametric sensor in our optical sensing arrangement.

在这项工作中，我们观察到壳聚糖-二氧化硅纳米颗粒复合膜 (CSNCM) 的不同物理特性和葡萄糖传感能力随孔径变化的变化。对于壳聚糖和 SiNp 粉尘的特定混合百分比，成功制造无变形、独立的膜形成是可能的。制备三种不同尺寸（NP1 ~ 100 nm、NP2 ~ 300 nm 和 NP3 ~ 500 nm）的二氧化硅纳米粒子以制备相应孔径（分别为 CM1、CM2 和 CM3）的 CSNCM。通过从顶层溶解二氧化硅纳米粒子，进行热 NaOH 蚀刻以在 CSNCM 基质中诱导表面孔隙。我们发现孔分布、表面形态、光学特性和介电特性在很大程度上取决于膜的孔径。对于葡萄糖传感表征，